A one to punch on the most sought after vitamins and nutrients as they relate to the immune function. These supplements highly support the immune system and its ability to combat external buggies. As an added bonus Zinca stop is just one for the cabinet. Which is the first line of defense to be used at the first sign of any change in immune system function. At the first sign of a scratchy through I take half of the bottle and that usually takes care of it. The rest of the supplements are meant to be taken on a daily basis as these are maintenance or in higher doses during a peak phase when you really want to optimize the immune system.